Please wait...

Canadian Pharmacists Association
Canadian Pharmacists Association
Facebook Share
Twitter Share
LinkedIn Share
Google Plus Share
Email Share

Compendium of Therapeutic Choices, 2019 Edition

Image of Compendium of Therapeutic Choices, 2019 EditionCTC is the trusted reference for Canada’s health care providers, guiding clinical decision making at the point of care by providing unbiased, evidence-based, practical information on hundreds of medical conditions.

Practical, bottom-line, clinical information covering more than 200 common medical conditions is referenced and organized in a concise format by therapeutic condition. More than 70 chapters cover drug therapy during pregnancy and breastfeeding. The content is based on the best available evidence, subject to a rigorous peer review process.

Here’s what’s new in CTC 2019:

  • Four new topics:
    • Lyme Disease
    • Medical Abortion
    • Viral Hepatitis — Acute
    • Viral Hepatitis — Chronic
  • All 130 chapters and 4 appendices reviewed
  • 60 chapters fully revised, updated and peer-reviewed
  • All drug tables completely revised and updated
Grey Canadian Icon
Canadian CTC 2019 contains unparalleled Canadian-specific content available in both official languages (French content available on digital formats only) written and reviewed by Canadian expert physicians and pharmacists and managed by CPhA editors.
Grey Current Icon
Current Digital content is updated weekly. Chapters and related content such as drug tables, figures, algorithms and appendices, are regularly reviewed and updated to reflect renewed evidence-based content. New to the 2019 print edition: Four new topics (Lyme Disease, Medical Abortion, Viral Hepatitis — Acute and Viral Hepatitis — Chronic); 60 chapters fully revised, updated and peer-reviewed including last peer review date to differentiate those with minor updates.
Grey Continuous Icon
Continuous Improvement Our content undergoes continuous review and improvement. CPhA employs a rigorous review process to ensure that the information is accurate and unbiased. Content is extensively reviewed and validated by skilled clinical editors, and by external physician and pharmacist reviewers who are recognized experts in their particular clinical areas.
Grey Convenient Icon
Convenient With the e-Suite bundle, you have easy access to recommended treatment information for more than 200 conditions on multiple platforms designed to suit the way you work. Now you can access therapeutic information whenever, wherever and however you want it.


Here's what the Canadian Pharmacist of the Year (2014), Prof. John Papastergiou, thinks of the Compendium of Therapeutic Choices:


Dr. Angela Hanlon
Pharmacology can become a tangled mess of un-useable information, depending on how it’s approached. Therapeutic Choices gives me  the necessary information in a way that I can remember.  What I can’t remember, I can quickly look up using my memory of the book’s layout. I would absolutely recommend it to a colleague.Dr. Angela Hanlon, Naturopath Doctor
Cindy Fehr
I use CTC on a regular basis to support clinical assessment, differential diagnoses, and decision making for conditions that may be common but are less commonly seen in my daily practice. I don’t have to search several resources to find information that is pertinent, up-to-date, and Canadian.  CTC is a quick refresher on what Canadian guidelines/recommendations I need to consider. It is a must have for novice and experience practitioners alike.—Cindy Fehr, Nurse Practitioner
Michael Kani
CTC covers a wide variety of disease states, the information is concise and useful, and it’s Canadian-focused. I use it as a reference to confirm dosing and treatment strategies, which is extremely helpful for a new practitioner. It gives me the assurance that the recommendation I’m making is supported by evidence, which is key in providing patient-focused care.” – Michael Kani, Pharmacist
Dr. Joel Weaver
The Canadian content of CTC is very important and is one of the primary reasons that I continue to buy CTC with each edition.  It is not easy to find a resource for the busy primary care clinician that is focused mainly on Canadian content and which is both easily accessed and evidence based.—Dr. Joel Weaver, M.D.
Dr. Céline Léger-Nolet
CTC is a trusted reference in the dissemination of accurate and up to date information. The content is excellent!  This book addresses a number of conditions I encounter on a daily basis in my internal medicine practice. I regularly have medical students and residents rotating through my office, and recommend CTC as a very valuable reference to have available.Dr. Céline Léger-Nolet, MD, FRCPC


Print: The Compendium of Therapeutic Choices print edition is familiar and reliable. You can highlight information, attach a Post-It note, write in the margins, etc., and it's very easy to find those notes later. But more importantly, it never needs a power source.

Online: This bilingual web-based version of the Compendium of Therapeutic Choices is updated weekly to ensure you have the most current information available.

Mobile: Find recommended treatments for more than 200 hundred conditions with Drug Choices (DC) in our RxTx Mobile App. Check doses, adverse effects, drug interactions and relative cost for over 2200 drugs. View all drug/classes to treat a specific condition.

Data Integration: Our therapeutic content can be easily integrated into any electronic medical record (EMR), electronic health record (EHR) and drug information system (DIS) for maximum functionality and usability. Learn more about data integration

Available Formats


List of conditions

Alterations in Body Temperature

  • Fever

Blood Disorders

  • Common Anemias
    • Iron-deficiency Anemia
    • Megaloblastic Anemia
    • Anemias Responsive to Pharmacologic Stimulation of Erythropoiesis

Cancer Chemotherapy Toxicity

  • Chemotherapy-induced Nausea and Vomiting
  • Management of Side Effects of Cancer Therapy and Radiation Therapy

Cardiovascular Disorders

  • Acute Coronary Syndromes
    • Unstable Angina (UA) and Non-ST Segment Elevation Myocardial Infarction (NSTEMI)
    • ST Segment Elevation Myocardial Infarction (STEMI)
  • Syncope
    • Vasovagal Syncope
    • Orthostatic Hypotension
  • Venous Thromboembolism
    • Treatment of Venous Thromboembolism
    • Prophylaxis of Venous Thromboembolism
  • Acute Stroke
  • Dyslipidemias
  • Heart Failure
  • Hypertension
  • Intermittent Claudication
  • Post-myocardial Infarction
  • Prevention of Ischemic Stroke
  • Primary Prevention of Vascular Disease
  • Raynaud's Phenomenon
  • Stable Angina
  • Supraventricular Tachycardia
  • Ventricular Tachyarrhythmias

Endocrine and Metabolic Disorders

  • Diabetes Mellitus
    • Type 1 and Type 2 Diabetes Mellitus
    • Preventing Type 2 Diabetes Mellitus
    • Diabetic Ketoacidosis
  • Thyroid Disorders
    • Hypothyroidism
    • Thyrotoxicosis
    • Thyroid Nodules and Goitre
  • Obesity

Eye Disorders

  • Age-related Macular Degeneration
  • Cataract Surgery Postoperative Care
  • Glaucoma
  • Red Eye

Fluid and Electrolyte Disorders

  • Potassium Disturbances
    • Hyperkalemia
    • Hypokalemia
  • Dehydration in Children
  • Edema
  • Hypercalcemia
  • Hypovolemia

Gastrointestinal Disorders

  • Chronic Liver Diseases
    • Ascites (Portal Hypertension)
    • Spontaneous Bacterial Peritonitis (SBP)
    • Hepatic Encephalopathy
    • Cholestatic Disease
    • Autoimmune Chronic Active Hepatitis
    • Alcoholic Liver Disease
    • Hemochromatosis
    • Wilson's Disease
  • Dyspepsia and Peptic Ulcer Disease
    • Uninvestigated Dyspepsia
    • Dyspepsia with Normal Endoscopy
    • Treatment of Peptic Ulcer Disease Due to Helicobacter pylori Infection
    • Prevention of Peptic Ulcer Disease During ASA/NSAID Therapy
    • Treatment of Peptic Ulcer Disease During ASA/NSAID Therapy
  • Viral Hepatitis Acute
    • Prevention of Viral Hepatitis
  • Viral Hepatitis Chronic
    • Chronic Hepatitis B
    • Chronic Hepatitis C
  • Inflammatory Bowel Disease
    • Crohn's Disease
    • Ulcerative Colitis
    • Ulcerative Proctosigmoiditis
  • Constipation in Adults
  • Diarrhea
  • Gastroesophageal Reflux Disease
  • Irritable Bowel Syndrome
  • Nausea in Adults
  • Upper Gastrointestinal Bleeding

Genitourinary Disorders

  • Urinary Incontinence in Adults
    • Stress Incontinence
    • Urge Incontinence
    • Mixed Incontinence
    • Chronic Retention of Urine
  • Lower Urinary Tract Symptoms and Benign Prostatic Hyperplasia
  • Urinary Incontinence in Children

Infectious Diseases

  • Infective Endocarditis—Management and Prevention
    • Treatment of Infective Endocarditis
    • Prevention of Infective Endocarditis
  • Influenza
    • Prevention
    • Treatment 
  • Travellers' Diarrhea
    • Prevention of Travellers' Diarrhea
    • Self-Treatment of Travellers' Diarrhea
  • Sexually Transmitted Infections
    • Infections Characterized by Vaginal Discharge
    • Infections Characterized by Urethritis and Cervicitis
    • Infections Characterized by Genital Ulcers
    • Management of Anogenital Warts
    • Management of Pelvic Inflammatory Disease
  • Herpesvirus Infections
    • Herpes Simplex Virus
    • Varicella-Zoster Virus
  • Acute Bronchitis
  • Acute Osteomyelitis
  • Acute Otitis Media in Childhood
  • Bacterial Meningitis
  • Community-Acquired Pneumonia
  • Diabetic Foot Infections
  • HIV Infection
  • Infections in the Cancer Patient
  • Malaria Prevention
  • Prevention and Treatment of Opportunistic Infections in HIV-positive Patients
  • Acute Rhinosinusitis
  • Group A Streptococcal Pharyngitis
  • Tuberculosis
  • Urinary Tract Infection
  • Lyme Disease

Musculoskeletal Disorders

  • Polymyalgia Rheumatica and Giant-Cell Arteritis
    • Polymyalgia Rheumatica (PMR)
    • Giant-Cell Arteritis (GCA)
  • Gout and Hyperuricemia
    • Asymptomatic Hyperuricemia
    • Acute Gouty Arthritis
    • Intercritical Period and Prophylaxis
    • Chronic Tophaceous Gout
  • Neck Pain and Whiplash
    • Acute Phase to 30 Days
    • Subacute Period (4-12 weeks)
    • Three Months
    • Chronic Neck Pain (6 months)
  • Low Back Pain
    • Acute Low Back Pain
    • Subacute and Recurrent Low Back Pain
    • Chronic Low Back Pain
  • Chronic Fatigue Syndrome
  • Fibromyalgia
  • Osteoarthritis
  • Osteoporosis
  • Rheumatoid Arthritis
  • Sports Injuries
  • Systemic Lupus Erythematosus

Neurologic Disorders

  • Headache in Children
    • Tension-type Headache
    • Medication-overuse Headache
    • Migraine
  • Acute Pain
  • Bell's Palsy
  • Chronic Spasticity
  • Headache in Adults
  • Multiple Sclerosis
  • Muscle Cramps
  • Neuropathic Pain
  • Parkinson Disease
  • Persistent Hiccups
  • Restless Legs Syndrome
  • Seizures and Epilepsy

Palliative Care

  • End-of-Life Care
    • Dyspnea
    • Pain
    • Terminal Delirium and Agitation
    • Respiratory Secretions

    Psychiatric Disorders

    • Eating Disorders
      • Anorexia Nervosa
      • Bulimia Nervosa
    • Acute Agitation
    • Anxiety Disorders
    • Attention-Deficit Hyperactivity Disorder
    • Bipolar Disorder
    • Dementia
    • Depression
    • Insomnia
    • Obsessive-Compulsive Disorder
    • Post-traumatic Stress Disorder
    • Psychoses
    • Tobacco Use Disorder: Smoking Cessation
    • Alcohol-Related Disorders
    • Opioid-Related Disorders
  • Renal Disorders

    • Chronic Kidney Disease

    Respiratory Disorders

    • Allergic Rhinitis
    • Asthma in Adults
    • Asthma in Infants and Children
    • Chronic Cough in Adults
    • Chronic Obstructive Pulmonary Disease
    • Croup
    • Viral Rhinitis

    Sexual Health Disorders

    • Female Sexual Dysfunction
      • Female Sexual Interest/Arousal Disorder
      • Female Orgasmic Disorder
      • Genito-Pelvic Pain/Penetration Disorder
    • Male Sexual Dysfunction
      • Erectile Dysfunction
      • Premature Ejaculation
      • Hypoactive Sexual Desire Disorder
      • Delayed Ejaculation
    • Endometriosis
      • Endometriosis-associated Pain
      • Endometriosis-associated Infertility
    • Contraception
    • Dysmenorrhea
    • Menopause
    • Heavy Menstrual Bleeding
    • Medical Abortion

    Skin Disorders

    • Psoriasis
      • Scalp
      • Face
      • Hands and Feet
      • Body and Extremities
      • Fold Areas
      • Nails
      • Severe or Resistant Psoriasis
    • Acne
    • Atopic Dermatitis
    • Bacterial Skin Infections
    • Burns
    • Fungal Nail Infections
    • Pressure Injuries and Ulcers
    • Pruritus
    • Rosacea
    • Scabies and Lice
    • Sunburn


    • Dosage Adjustment in Renal Impairment
    • Drug Use During Breastfeeding
    • Drug Use During Pregnancy
    • Nutritional Supplements



Editorial Policy

Each therapeutic topic from CTC and CTMA is written by an expert author and is based on the best available evidence. CPhA employs a rigorous review process to ensure that the information is accurate and unbiased. Content is extensively reviewed and validated by skilled CPhA clinical editors and by external reviewers who are recognized experts (physicians and pharmacists) in their particular clinical area.

CPhA asks authors to disclose any potential conflicts of interest. CPhA does not accept funding from pharmaceutical manufacturers for any content that we develop.