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Compendium of Therapeutic Choices

CTC 2014 - Compendium of Therapeutic ChoicesThe Compendium of Therapeutic Choices, formerly Therapeutic Choices, is a trusted Canadian source for evidence-based treatment information for all health care practitioners involved in therapeutic decision-making.  Practical, bottom-line, clinical information covering more than 200 common medical conditions is referenced and organized in a concise format by therapeutic condition. More than 72 chapters cover drug therapy during pregnancy and breastfeeding. The content is based on the best available evidence, subject to a rigorous peer review process. [en francais]

Canadian The Compendium of Therapeutic Choices contains unparalleled Canadian-specific content available in both official languages written and reviewed by Canadian expert physicians and pharmacists and managed by CPhA editors.


Current Digital content is updated every two weeks. The latest print edition published in August 2014, has been completely revised and features three new chapters (obsessive-compulsive disorder, post-traumatic stress disorder and menorrhagia). 


Continuous Improvement The content undergoes continuous review and improvement. In addition to our own ongoing surveillance of the evidence, our partnership with McGill University provides direct feedback from physicians and pharmacists. McGill researchers select potentially actionable feedback, provide it to CPhA for consideration, and track the rate of content change prompted by the feedback. Learn more in the Canadian Family Physician article “Better-than-best” evidence? Using family physicians’ feedback for 2-way knowledge translation.


Convenient With the e-Suite bundle, you have easy access to recommended treatment information for more than 200 conditions on multiple platforms designed to suit the way you work. Now you can access therapeutic information whenever, wherever and however you want it.



Here's what the Canadian Pharmacist of the Year (2014), John Papastergiou, thinks of the Compendium of Therapeutic Choices:



Pharmacology can become a tangled mess of un-useable information, depending on how it’s approached.  Therapeutic Choices gives me  the necessary information in a way that I can remember.  What I can’t remember, I can quickly look up using my memory of the book’s layout. I would absolutely recommend it to a colleague.Angela Hanlon, Naturopath Doctor


I use CTC7 on a regular basis to support clinical assessment, differential diagnoses, and decision making for conditions that may be common but are less commonly seen in my daily practice. I don’t have to search several resources to find information that is pertinent, up-to-date, and Canadian.  CTC7 is a quick refresher on what Canadian guidelines/recommendations I need to consider. It is a must have for novice and experience practitioners alike.—Cindy Fehr, Nurse Practitioner


CTC helps me provide efficient patient care. I use it three to four times a day. The new evidence level feature is amazing and it makes me feel more confident about the decisions and recommendations I make. It’s a must-have reference for all students and health care providers.—Maitrik Patel, Pharmacist


CTC7 covers a wide variety of disease states, the information is concise and useful, and it’s Canadian-focused. I use it as a reference to confirm dosing and treatment strategies, which is extremely helpful for a new practitioner. It gives me the assurance that the recommendation I’m making is supported by evidence, which is key in providing patient-focused care.” – Michael Kani, Pharmacist


The Canadian content of CTC is very important and is one of the primary reasons that I continue to buy CTC with each edition.  It is not easy to find a resource for the busy primary care clinician that is focused mainly on Canadian content and which is both easily accessed and evidence based.—Dr. Joel Weaver, M.D.


CTC is a trusted reference in the dissemination of accurate and up to date information. The content is excellent!  This book addresses a number of conditions I encounter on a daily basis in my internal medicine practice. I regularly have medical students and residents rotating through my office, and recommend CTC as a very valuable reference to have available.Dr. Céline Léger-Nolet, M.D.



Print: The Compendium of Therapeutic Choices print edition is familiar and reliable. You can add notes and highlights easily, and it doesn’t need a power source. Read a sample chapter: Hypertension

Online: This bilingual web-based version of the Compendium of Therapeutic Choices is updated bi-weekly to ensure you have the most current information available.

Mobile: Find recommended treatments for more than 200 hundred conditions with Drug Choices in our RxTx Mobile App. Check doses, adverse effects, drug interactions and relative cost for over 2200 drugs. View all drug/classes to treat a specific condition. View a sample of the mobile app

Data Integration: Our therapeutic content can be easily integrated into any electronic medical record (EMR), electronic health record (EHR) and drug information system (DIS) for maximum functionality and usability. Learn more about data integration

Available Formats


  • e-suite includes online and mobile $179 (Buy Now)
  • Print $199 (Buy Now)
  • Print and e-suite (all access) includes print, online, mobile $199  (Buy Now)

List of conditions

Blood Disorders

  • Common Anemias
    • Iron-deficiency Anemia
    • Megaloblastic Anemia
    • Anemias Responsive to Pharmacologic Stimulation of Erythropoiesis

Cancer Chemotherapy Toxicity

  • Chemotherapy-induced Nausea and Vomiting
  • Management of Side Effects of Chemotherapy and Radiation Therapy

Cardiovascular Disorders

  • Acute Coronary Syndromes
    • Unstable Angina (UA) and Non-ST Segment Elevation Myocardial Infarction (NSTEMI)
    • ST Segment Elevation Myocardial Infarction (STEMI)
  • Syncope
    • Vasovagal Syncope
    • Orthostatic Hypotension
  • Venous Thromboembolism
    • Treatment of Venous Thromboembolism
    • Prophylaxis of Venous Thromboembolism
  • Acute Stroke
  • Dyslipidemias
  • Heart Failure
  • Hypertension
  • Intermittent Claudication
  • Post-myocardial Infarction
  • Prevention of Ischemic Stroke
  • Primary Prevention of Vascular Disease
  • Raynaud's Phenomenon
  • Stable Angina
  • Supraventricular Tachycardia
  • Ventricular Tachyarrhythmias

Endocrine and Metabolic Disorders

  • Diabetes Mellitus
    • Type 1 and Type 2 Diabetes Mellitus
    • Preventing Type 2 Diabetes Mellitus
    • Diabetic Ketoacidosis
  • Thyroid Disorders
    • Hypothyroidism
    • Hyperthyroidism
    • Thyroid Nodules and Goitre
  • Obesity

End-of-Life Care

  • End-of-Life Care
    • Dyspnea
    • Pain
    • Terminal Delirium and Agitation
    • Respiratory Secretions

Eye Disorders

  • Age-related Macular Degeneration
  • Cataract Surgery Postoperative Care
  • Glaucoma
  • Red Eye

Fluid and Electrolyte

  • Potassium Disturbances
    • Hyperkalemia
    • Hypokalemia
  • Dehydration in Children
  • Edema
  • Hypercalcemia
  • Hypovolemia

Gastrointestinal Disorders

  • Chronic Liver Diseases
    • Ascites (Portal Hypertension)
    • Spontaneous Bacterial Peritonitis (SBP)
    • Hepatic Encephalopathy
    • Cholestatic Disease
    • Autoimmune Chronic Active Hepatitis
    • Alcoholic Liver Disease
    • Hemochromatosis
    • Wilson's Disease
  • Dyspepsia and Peptic Ulcer Disease
    • Uninvestigated Dyspepsia
    • Dyspepsia with Normal Endoscopy
    • Treatment of Peptic Ulcer Disease Due to Helicobacter pylori Infection
    • Prevention of Peptic Ulcer Disease in ASA/NSAID Users
    • Treatment of Peptic Ulcer Disease in ASA/NSAID Users
  • Viral Hepatitis
    • Prevention of Viral Hepatitis
    • Acute Viral Hepatitis
    • Chronic Hepatitis B
    • Chronic Hepatitis C
  • Inflammatory Bowel Disease
    • Crohn's Disease
    • Ulcerative Colitis
    • Ulcerative Proctosigmoiditis
  • Constipation in Adults
  • Diarrhea
  • Gastroesophageal Reflux Disease
  • Irritable Bowel Syndrome
  • Nausea in Adults
  • Upper Gastrointestinal Bleeding

Genitourinary Disorders

  • Urinary Incontinence in Adults
    • Stress Incontinence
    • Urge Incontinence
    • Mixed Incontinence
    • Chronic Retention of Urine
  • Lower Urinary Tract Symptoms and Benign Prostatic Hyperplasia
  • Urinary Incontinence in Children

Infectious Diseases

  • Infective Endocarditis—Management and Prevention
    • Treatment of Infective Endocarditis
    • Prevention of Infective Endocarditis
  • Influenza
    • Prevention
    • Treatment 
  • Travellers' Diarrhea
    • Prevention
    • Self-Treatment
  • Sexually Transmitted Infections
    • Infections Characterized by Vaginal Discharge
    • Infections Characterized by Urethritis and Cervicitis
    • Infections Characterized by Genital Ulcers
    • Management of Anogenital Warts
    • Management of Pelvic Inflammatory Disease
  • Herpesvirus Infections
    • Herpes Simplex Virus
    • Varicella-Zoster Virus
  • Acute Bronchitis
  • Acute Osteomyelitis
  • Acute Otitis Media in Childhood
  • Bacterial Meningitis
  • Community-acquired Pneumonia
  • Diabetic Foot Infections
  • HIV Infection
  • Infections in the Cancer Patient
  • Malaria Prevention
  • Opportunistic Infections in HIV-positive Patients
  • Sepsis and Septic Shock
  • Sinusitis
  • Streptococcal Sore Throat
  • Tuberculosis
  • Urinary Tract Infection

Musculoskeletal Disorders

  • Polymyalgia Rheumatica and Giant-Cell Arteritis
    • Polymyalgia Rheumatica (PMR)
    • Giant-Cell Arteritis (GCA)
  • Gout and Hyperuricemia
    • Asymptomatic Hyperuricemia
    • Acute Gouty Arthritis
    • Intercritical Period and Prophylaxis
    • Chronic Tophaceous Gout
  • Neck Pain and Whiplash
    • Acute Phase to 30 Days
    • During Second and Third Month (Subacute Phase)
    • By 6 Months or More (Chronic Neck Pain)
  • Low Back Pain
    • Acute Low Back Pain
    • Subacute and Recurrent Low Back Pain
    • Chronic Low Back Pain
  • Chronic Fatigue Syndrome
  • Fibromyalgia
  • Osteoarthritis
  • Osteoporosis
  • Rheumatoid Arthritis
  • Sports Injuries
  • Systemic Lupus Erythematosus

Neurologic Disorders

  • Headache in Children
    • Tension-type Headache
    • Medication-overuse Headache
    • Migraine
  • Thermoregulatory Disorders in Adults
    • Hyperthermia
    • Hypothermia
  • Acute Pain
  • Bell's Palsy
  • Chronic Spasticity
  • Fever in Children
  • Headache in Adults
  • Multiple Sclerosis
  • Muscle Cramps
  • Neuropathic Pain
  • Parkinson's Disease
  • Persistent Hiccups
  • Restless Legs Syndrome
  • Seizures and Epilepsy

Psychiatric Disorders

  • Eating Disorders
    • Anorexia Nervosa
    • Bulimia Nervosa
  • Acute Agitation
  • Anxiety Disorders
  • Attention-Deficit Hyperactivity Disorder
  • Bipolar Disorder
  • Dementia
  • Depression
  • Drug Withdrawal Syndromes
  • Insomnia
  • Obsessive-Compulsive Disorder
  • Post-traumatic Stress Disorder
  • Psychoses
  • Smoking Cessation

Renal Disorders

  • Chronic Kidney Disease

Respiratory Disorders

  • Allergic Rhinitis
  • Asthma in Adults
  • Asthma in Infants and Children
  • Chronic Cough in Adults
  • Chronic Obstructive Pulmonary Disease
  • Croup
  • Viral Rhinitis

Sexual Health

  • Female Sexual Dysfunction
    • Female Sexual Interest/Arousal Disorder
    • Female Orgasmic Disorder
    • Genito-Pelvic Pain/Penetration Disorder
  • Male Sexual Dysfunction
    • Erectile Dysfunction
    • Premature Ejaculation
    • Hypoactive Sexual Desire Disorder
  • Endometriosis
    • Endometriosis-associated Pain
    • Endometriosis-associated Infertility
  • Contraception
  • Dysmenorrhea
  • Menopause
  • Menorrhagia

Skin Disorders

  • Psoriasis
    • Scalp
    • Face
    • Hands and Feet
    • Body and Extremities
    • Fold Areas
    • Nails
    • Severe or Resistant Psoriasis
  • Acne
  • Atopic Dermatitis
  • Bacterial Skin Infections
  • Burns
  • Fungal Nail Infections
  • Pressure Ulcers
  • Pruritus
  • Rosacea
  • Scabies and Lice
  • Sunburn

Drug Use During Pregnancy

Drug Use During Breastfeeding

Nutritional Supplements

Dosage Adjustment in Renal Impairment

Editorial Policy

Each therapeutic topic from CTC and CTMA is written by an expert author and is based on the best available evidence. CPhA employs a rigorous review process to ensure that the information is accurate and unbiased. Content is extensively reviewed and validated by skilled CPhA clinical editors and by external reviewers who are recognized experts (physicians and pharmacists) in their particular clinical area.

CPhA asks authors to disclose any potential conflicts of interest. CPhA does not accept funding from pharmaceutical manufacturers for any content that we develop.